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目的观察康泉、灭吐灵、地塞本松联合应用时18例卵巢癌40人次以顺铂为主的联合化疗所产生的恶心、呕吐作预防性治疗。方法康泉3mg溶于生理盐水40ml缓慢静注、灭吐灵10mg、地塞米松5mg肌注，半小时后开始化疗，化疗结束后半小时重复使用后两种药。24小时记录恶心、呕吐次数及程度、连续7天。结果O度：22人次，I度：15人次，止吐有效率92．5％（37／40）。急性呕吐有效率92．5％（37／40），延迟期呕吐有效率95％（38／40）均高于文献报导的单独用康泉或灭吐灵止吐有效率。结论康泉、灭吐灵、地塞米松联合镇吐有效可行，且用量小，副作用少。
Objective To observe the nausea and vomiting caused by combination chemotherapy of Kangquan, Qutuolin, and dexamethasone in 40 cases of ovarian cancer with 40 times of cisplatin as the preventive treatment. Methods Kangquan 3 mg dissolved in normal saline 40 ml slow intravenous injection, metoclopramide 10 mg, dexamethasone 5 mg intramuscular injection, half an hour later began chemotherapy, half an hour after the end of chemotherapy after repeated use of the two drugs. Nausea, vomiting, and degree were recorded for 24 consecutive hours for 7 consecutive days. Results: O degrees: 22 visits, I degree: 15 visits, antiemetic effectiveness 92.5% (37/40). The effective rate of acute vomiting was 92.5% (37/40), and the effective rate of vomiting in delayed period 95% (38/40) was higher than that reported in the literature alone for Kangquan or Jietuling. Conclusion The combination of Kangquan, Jietuling and dexamethasone is effective and effective, and the dosage is small and the side effects are less.