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本文报道川南地区80年代初至90年代初3595例住院患者肺部感染病原菌变迁。结果检出菌株7481株，院外感染占62．4％，院内感染占37．6％。G＋细菌占55．2％，G－细菌41．4％，霉菌占3．4％。80年代初至90年代初G＋细茵由68．7％降至38．5％，G－杆菌由28．4％上升到65．9％，P均＜0．05，及时多次痰培养＋药敏试验是病原诊断及指导用药的最佳方法．
This article reports the changes of pathogenic bacteria of lung infection in 3595 hospitalized patients from the early 1980s to the early 1990s in South China. Results A total of 7481 isolates were detected, accounting for 62.4% of nosocomial infections and 37.6% of nosocomial infections. G + bacteria accounted for 55.2%, G-bacteria 41.4%, mold accounted for 3.4%. From the early 1980s to the early 1990s, the G + sperms decreased from 68.7% to 38.5%, while the G - bacteria increased from 28.4% to 65.9%, P <0.05, Susceptibility testing is the best way to diagnose and guide pathogen.