目的研究B超定位引导下经皮穿刺置管引流术(PCD)用于治疗急性胰腺炎伴早期巨大胰腺假性囊肿(PPC)形成的临床疗效。方法回顾分析52例重症急性胰腺炎(SAP)伴早期巨大PPC患者的临床资料,采用PCD治疗,观察临床治疗效果。结果 52例患者均获得穿刺置管成功,其中50例(96.15%)一次性穿刺成功;PCD完全治愈28例(53.85%),另34例获得进一步手术条件并成功实施内引流术后获得治愈。结论对SAP伴早期巨大PPC患者实施PCD治疗能够快速有效地改善临床症状,促进囊肿缩小或者消失,为进一步治疗创造有利条件。 Objective To study the clinical effect of percutaneous catheter drainage (PCD) guided by B-positioning in the treatment of acute pancreatitis with early giant pancreatic pseudocysts (PPC). Methods The clinical data of 52 patients with severe acute pancreatitis (SAP) complicated with early huge PPC were retrospectively analyzed. The therapeutic effect was observed by PCD. Results All the 52 patients were successful in puncture and catheterization. Fifty patients (96.15%) were successfully punctured at one time. PCD was completely cured in 28 patients (53.85%), and the other 34 patients underwent further operation and were cured after internal drainage. Conclusions The PCD treatment of SAP patients with early giant PPC can improve the clinical symptoms quickly and effectively, reduce or disappear the cyst, and create favorable conditions for further treatment.