病毒突变、有益和有害的宿主免疫应答及免疫功能改变三者作用相结合形成了人类免疫缺陷症病毒（HIV）感染的发病机理和结果。了解乙型肝炎（HB）和麻疹能有助于了解HIV。持续性乙型肝炎病毒（HBV）感染的临床缓解和加剧取决于病毒突变、诱导无反应性及宿主免疫应答三者的状况。麻疹病毒感染的多种细胞与HIV感染相同,并可引起免疫缺陷,但通常可自然恢复。比较研究获得的知识有助于确定HIV感染和艾滋病的免疫预防和治疗的方法和策略。 Mutation of viruses, beneficial and detrimental host immune responses, and changes in immune function combine to form the pathogenesis and outcome of human immunodeficiency virus (HIV) infection. Understanding Hepatitis B (HB) and measles can help understand HIV. The clinical remission and exacerbation of persistent hepatitis B virus (HBV) infection depend on the status of the virus mutation, induction of anergy and host immune response. The multiplicity of cells infected with measles virus are the same as those infected with HIV and can cause immunodeficiency but usually recover naturally. The comparative study of the knowledge gained helps to identify methods and strategies for immunization and HIV prevention and treatment.