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目的:探讨缬沙坦与氨氯地平联合用药治疗原发性高血压的临床疗效。方法:将我院住院治疗的150例原发性高血压患者随机成A、B两组,A组采用缬沙坦(80mg/d)与氨氯地平(5mg/d)联合用药要治疗,B组采用氨氯地平(5mg/d)治疗,在治疗5周后评价2组患者临床治疗疗效。结果:A组患者血压控制情况明显优于B组,A组血压达标率高于B组,A组血压达标率为56.2%,B组血压达标率41.5%,两组患者临床疗效比差异具有统计学意义(P<0.05)。结论:缬沙坦与氨氯地平联合用药治疗原发性高血压的血压达标率明显高于单独应用氨氯地平,临床疗效显著,值得推广。
Objective: To investigate the clinical efficacy of valsartan combined with amlodipine in the treatment of essential hypertension. Methods: A total of 150 patients with essential hypertension were randomly divided into A and B groups. Group A was treated with combination of valsartan (80mg / d) and amlodipine (5mg / d), and group B Group treated with amlodipine (5mg / d), 5 weeks after treatment, evaluation of two groups of patients with clinical curative effect. Results: The blood pressure control in group A was significantly better than that in group B. The blood pressure compliance rate in group A was higher than that in group B. The blood pressure compliance rate was 56.2% in group A and 41.5% in group B. The differences in clinical efficacy between the two groups were statistically significant Significance (P <0.05). Conclusion: The combination of valsartan and amlodipine in the treatment of essential hypertension blood pressure compliance rate was significantly higher than the single application of amlodipine, a significant clinical effect, it is worth promoting.