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１９６３～１９９７年共收治１０１例原发性甲状旁腺机能亢进症。临床特点为：病人年龄较轻，平均３４岁。骨病发生率高且严重，纤维囊性骨炎占６３３％。肾结石、肾钙化少，占３７６％。约４０％病人血钙不高或持续正常。术前颈部查体扪及肿物者１８例，１７例正确。间接定位体征５例均为阳性。这些病例均病程较长，腺体较大，最重１３ｇ，血钙均＞１２００ｍｇ／Ｌ。本组病理学特点腺瘤占９１例，腺癌６例，增生１例。比较了Ｂ超、ＣＴ、９９ｍＴｃＭＩＢＩ在术前定位诊断中的价值。结果表明，Ｂ超、ＣＴ、９９ｍＴｃＭＩＢＩ的灵敏性分别为４５％、８５％、９１％。特异性为９５％、９７％、１００％。准确性为８２％、９４％、９７％。目前在国内此类病例尚少，尤其是对再次手术者，这些非创伤性术前定位检查是有必要的。本组９８例探查，９６例获成功，手术成功率为９７９％。
From 1963 to 1997, a total of 101 cases of primary hyperparathyroidism were treated. Clinical features are: The patient is younger, with an average of 34 years. The incidence of bone disease is high and serious, fibrosangitis accounted for 63 3%. Kidney stones, less renal calcification, accounting for 37 6%. About 40% of patients with low or normal serum calcium. Preoperative neck palpable palpable mass in 18 cases, 17 cases were correct. Indirect positioning signs in 5 cases were positive. These cases have a longer duration, larger glands, the heaviest 13g, serum calcium were> 1200mg / L. This group of pathological features of adenomas in 91 cases, 6 cases of adenocarcinoma, hyperplasia in 1 case. The diagnostic value of B-ultrasonography, CT, 99mTc-MIBI in preoperative localization was compared. The results showed that the sensitivity of B-ultrasound, CT, 99mTc -MIBI were 45%, 85%, 91%. Specificity was 95%, 97%, 100%. Accuracy of 82%, 94%, 97%. At present, there are still few such cases in China, especially for re-operation, these non-invasive preoperative localization check is necessary. The group of 98 cases of exploration, 96 cases were successful, the success rate of 97.9% surgery.