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目的分析产前超声检查诊断胎儿单脐动脉结合胎儿染色体核型分析对孕妇进行正确的产前咨询的价值。方法回顾性分析2011年1-12月在宁夏医科大学总医院行超声检查发现的18例单脐动脉,对其超声特征、胎儿染色体核型、产前咨询建议、妊娠结局进行随访分析。结果 18例胎儿单脐动脉病例中,其中16例单胎妊娠,2例双胎妊娠;9例单纯性单脐动脉,9例单脐动脉合并其他系统胎儿发育异常,其中染色体异常2例。随访结果中9例单纯性单脐动脉孕足月分娩,新生儿正常,8例引产,1例失访。结论单纯单脐动脉大多预后良好,产前咨询建议继续妊娠、定期随访;单脐动脉合并多发畸形者,若合并染色体异常,建议终止妊娠。临床医师应对胎儿单脐动脉进行正确的产前咨询,做好孕妇的孕期保健工作。
Objective To analyze the value of prenatal ultrasonography in diagnosing pregnant women with single prenatal counseling for diagnosis of unilateral umbilical artery and fetal karyotype analysis. Methods 18 cases of single umbilical artery found by ultrasound examination at General Hospital of Ningxia Medical University from January to December in 2011 were retrospectively analyzed. The ultrasound features, fetal karyotype, prenatal advice and pregnancy outcome were analyzed retrospectively. Results 18 cases of unilateral umbilical artery in fetus, of which 16 cases of singleton pregnancy, 2 cases of twin pregnancy; 9 cases of simple umbilical artery, 9 cases of single umbilical artery combined with other systems of fetal dysplasia, including 2 cases of chromosomal abnormalities. Follow-up results in 9 cases of simple umbilical artery full-term pregnancy, normal newborns, 8 cases of induced labor, 1 case lost. Conclusions Most simple umbilical arteries have a good prognosis. Prenatal counseling is recommended for continued pregnancy and regular follow-up. Single umbilical artery complicated with multiple deformities, if the combined chromosomal abnormalities, it is recommended termination of pregnancy. Clinicians should be the fetus single umbilical artery for the correct antenatal counseling, good pregnant women during pregnancy health care.