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脑血管扩张药缺血性脑血管疾病应用扩血管药,可使缺血所引起的痉挛性血管扩张,并促进侧枝循环,从而增加脑血流量和改善脑循环。1.肉桂苯哌嗪(脑益嗪;Cinnarizine)其药理作用似罂粟碱,能直接扩张血管平滑肌,使血管扩张,对组胺、5-羟色胺、肾上腺素和缓激肽等生理活性物质有一定的拮抗作用。临床研究表明,其脑血管扩张作用很强,能显著地增加脑血流量,改善脑循环。我国临床用于脑动脉硬化症、脑血管痉挛、脑血栓形成、脑出血恢复期、钩端螺旋体脑动脉炎、内耳眩晕症、冠状动脉硬化症等疗效显著。口服:25～50毫克/次,1日3次。静脉缓注:20～40毫克/次。
Application of vasodilators in the treatment of ischemic cerebrovascular diseases of the cerebral vasodilators can cause spasmodic vasodilation caused by ischemia and promote collateral circulation, thereby increasing cerebral blood flow and improving cerebral circulation. Cinarizine (cinnarizine; Cinnarizine) its pharmacological effects like papaverine, can directly dilate vascular smooth muscle, the vasodilation, histamine, 5-hydroxytryptamine, epinephrine and bradykinin and other physiologically active substances have a certain Antagonism. Clinical studies have shown that its role in cerebral vasodilation strong, can significantly increase cerebral blood flow, improve cerebral circulation. Our clinical clinical cerebral atherosclerosis, cerebral vasospasm, cerebral thrombosis, cerebral hemorrhage recovery, leptospirosis, arteriosclerosis of the inner ear, vertigo, coronary atherosclerosis and other significant effect. Oral: 25 ~ 50 mg / time, 3 times on the 1st. Slow intravenous injection: 20 to 40 mg / time.