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目的观察肾综合征出血热实验室指标变化特点。方法采取回顾性调查方法,对40例肾综合征出血热患者在各型、各期中血小板(PLT)、降钙素原(PCT)、白细胞(WBC)、凝血酶原时间(PT)、肌酸激酶/乳酸脱氢酶(CK/LDH)等指标进行分析总结。结果 PLT下降程度、PCT升高程度与疾病严重程度呈正相关。WBC、PT、CK/LDH与疾病严重程度无明显相关性。PCT升高程度与病期进展呈负相关。WBC、PLT、中性粒细胞(N)与病情进展无明显相关性。感染组PCT高于非感染组,但两者WBC组间比较无明显差异。结论 PCT升高程度、PLT下降程度可作为肾综合征出血热早期的分型依据,PCT可以反映患者的病期进展,并可作为判断预后的指标。
Objective To observe the changes of laboratory indexes of hemorrhagic fever with renal syndrome. Methods A retrospective study was conducted on 40 cases of hemorrhagic fever with renal syndrome in various types and stages of platelet (PLT), procalcitonin (PCT), white blood cell (WBC), prothrombin time (PT), muscle Acid kinase / lactate dehydrogenase (CK / LDH) and other indicators were analyzed and summarized. Results The decrease of PLT and the increase of PCT were positively correlated with the severity of the disease. WBC, PT, CK / LDH and disease severity no significant correlation. The degree of progression of the PCT was negatively correlated with the progression of the disease. WBC, PLT, neutrophils (N) and disease progression no significant correlation. The infection group PCT was higher than the non-infected group, but there was no significant difference between the two WBC groups. Conclusions The level of PCT and the degree of decrease of PLT can be used as the basis of early stage of hemorrhagic fever with renal syndrome. PCT can reflect the stage of disease and can be used as an index to judge the prognosis.