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目的探讨糖尿病患者血糖对心脑血管的影响。方法收集心内科、神经内科住院收治并符合冠状动脉粥样硬化性心脏病、缺血性或出血性脑血管病诊断标准的226例患者作为研究对象,分析其糖代谢状况。结果全体研究对象中,经FPG和OGTT试验确诊符合糖尿病诊断标准者105例(46.5%),IGR检出率为30.1%(68/226),总的糖代谢异常患病率为76.6%;冠心病、脑血管病患者合并DM的风险均显著高于IGR、NGT患者(P<0.05或0.01)。结论冠心病、脑血管病患者糖代谢异常和糖尿病的发生率均显著高于普通人群,糖尿病血糖及糖代谢状态可作为心脑血管疾病预后的重要指标临床应用。
Objective To investigate the effect of blood sugar on cardiovascular and cerebrovascular in diabetic patients. Methods A total of 226 patients admitted to our hospital for cardiology and neurology admitted to hospital and meeting the diagnostic criteria of coronary atherosclerotic heart disease, ischemic or hemorrhagic cerebrovascular disease were enrolled in this study. Their glycometabolism status was analyzed. Results All the subjects were diagnosed by FPG and OGTT in 105 cases (46.5%) with diagnostic criteria of diabetes mellitus, the detection rate of IGR was 30.1% (68/226), and the prevalence of abnormal glucose metabolism was 76.6% Patients with heart disease and cerebrovascular disease had a significantly higher risk of DM than those with IGR and NGT (P <0.05 or 0.01). Conclusions The incidences of abnormal glucose metabolism and diabetes are significantly higher in patients with coronary heart disease and cerebrovascular disease than those in the general population. The status of diabetes mellitus and glucose metabolism can be used as an important index for prognosis of cardiovascular and cerebrovascular diseases.