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目的研究氯吡格雷联合氟伐他汀治疗脑梗死的临床疗效。方法选择2013年2月至2015年2月洛阳市第六人民医院收治的88例脑梗死患者作为研究对象,将其随机分为对照组和观察组,每组44例。对照组患者采用常规治疗法,观察组患者在常规治疗法的基础上加用氯吡格雷和氟伐他汀,比较两组治疗效果。结果观察组患者总有效率为97.73%,显著高于对照组的81.82%;观察组患者各项血脂指标改善程度均优于对照组,且观察组患者神经功能损伤和生活能力评分均显著优于对照组,差异均有统计学意义(P均<0.05)。结论氯吡格雷与氟伐他汀联用能有效提高脑梗死的治疗效果,降低患者的血脂水平,减少患者神经功能损伤,提高其生活能力,安全性好,实用性高,值得临床推荐。
Objective To study the clinical effect of clopidogrel combined with fluvastatin on cerebral infarction. Methods Eighty-eight patients with cerebral infarction admitted to the Sixth People’s Hospital of Luoyang from February 2013 to February 2015 were randomly divided into control group and observation group, with 44 cases in each group. Patients in the control group were treated with conventional therapy. Patients in the observation group were treated with clopidogrel and fluvastatin on the basis of conventional treatment, and the therapeutic effect was compared between the two groups. Results The total effective rate of the observation group was 97.73%, which was significantly higher than that of the control group (81.82%). In the observation group, the improvement of various blood lipid indexes was better than that of the control group, and the neurological impairment and life ability score of the observation group were significantly better than those of the control group Control group, the difference was statistically significant (P all <0.05). Conclusion Clopidogrel combined with fluvastatin can effectively improve the therapeutic effect of cerebral infarction, reduce the level of blood lipid in patients, reduce the neurological impairment and improve the living ability of patients. The safety and practicality are worthy of clinical recommendation.