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目的:探讨矽肺合并慢性肺源性心脏病应用果糖二磷酸钠治疗的疗效。方法:对58例矽肺合并慢性肺源性心脏病患者随机分为对照组和治疗组。对照组:给予持续性低流量吸氧,祛痰、止咳平喘合并感染时加用抗生素的常规治疗;治疗组:在常规治疗的基础上加用果糖二磷酸钠。结果:治疗组与对照组治疗后动脉血气分析及临床症状有统计学差异(P<0.05)。治疗组总有效率93.1%,高于对照组79.3%。结论:果糖二磷酸钠治疗矽肺合并慢性肺源性心脏病的疗效显著。
Objective: To investigate the therapeutic effect of fructose-bisphosphate on silicosis and chronic cor pulmonale. Methods: 58 patients with silicosis and chronic cor pulmonale were randomly divided into control group and treatment group. Control group: given continuous low-flow oxygen, expectorant, cough and asthma combined infection with antibiotics routine treatment; treatment group: in the conventional treatment based on the use of fructose diphosphate. Results: Arterial blood gas analysis and clinical symptoms in the treatment group and the control group were statistically different (P <0.05). The total effective rate was 93.1% in the treatment group, 79.3% higher than the control group. Conclusion: The therapeutic effect of fructose diphosphate on silicosis complicated with chronic cor pulmonale is significant.