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目的观察全身热疗对晚期肿瘤患者肺水肿形成的影响。作者对16例晚期肿瘤患者(肺癌7例、胃癌2例、原发性肝癌2例、食道癌1例、结肠癌3例、胰腺癌1例)进行全身热疗。方法采用体外循环的方法,即从股动脉插管引出血液泵入热交换器循环加热后,再从股静脉输入,动态监测食道和直肠温度,当中心体温达到41.8℃～42℃时,降低循环加热的血液温度,缓慢升温至42.5℃时维持50min以上。结果肺癌5例、胃癌1例、原发性肝癌1例出现肺水肿。结论全身热疗容易导致肺水肿。
Objective To observe the effect of systemic hyperthermia on pulmonary edema in advanced cancer patients. The authors performed systemic hyperthermia on 16 patients with advanced cancer (7 lung cancer, 2 gastric cancer, 2 primary liver cancer, 1 esophageal cancer, 3 colon cancer and 1 pancreatic cancer). Methods The method of extracorporeal circulation was used. The blood was drawn from the femoral artery into the heat exchanger and then circulated through the femoral vein. The temperature of esophagus and rectum was monitored dynamically. When the central temperature reached 41.8 ℃ ~ 42 ℃, the circulation was reduced Heated blood temperature, slowly warming to 42.5 ℃ to maintain more than 50min. Results Five cases of lung cancer, one case of gastric cancer and one case of primary liver cancer showed pulmonary edema. Conclusion Whole body hyperthermia easily lead to pulmonary edema.