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女孩,第一胎,孕38周。母因早破水90分钟入院,羊水为黄色粘稠,来院时胎心不规则,经吸氧后胎心转好,行剖宫产。生后青紫窒息,吸痰后啼哭,出生体重2850g。母28岁,孕期健康。未接受过放射线及化学药物,父母非近亲婚配。生后查体:外貌呈先天愚型样,皮肤有散在出血点,心音有力,未闻杂音,肝肋下7cm延到左腹与脾相连、质硬,表面光滑。脾肋下3cm。给庆大霉素肌注,生后4小时呼吸急促,给氧,于生后36小时发绀明显。呼吸心跳先后停止。病理结果:(1)多脏器巨核细胞浸润,肝、心、肺、肾、脑、胰有大量幼稚不成熟
Girl, first child, 38 weeks pregnant. Mothers because of broken water for 90 minutes admission, amniotic fluid yellow viscous, irregular fetal heart rate to the hospital, fetal heart rate after oxygen transfer, cesarean section. After birth purple suffocation, after crying suction, birth weight 2850g. Female 28 years old, healthy during pregnancy. Did not receive radiation and chemical drugs, parents non-relatives marriage. Physical examination after birth: appearance of Down’s syndrome, the skin has scattered bleeding point, strong heart sounds, unheard noise, hepatic ribs 7cm extended to the left and the spleen connected, hard, smooth surface. Spleen ribs 3cm. To gentamycin intramuscular injection, 4 hours after birth, shortness of breath, oxygen, cyanosis significantly 36 hours after birth. Respiratory heartbeat has stopped. Pathological results: (1) multinomial megakaryocyte infiltration, liver, heart, lung, kidney, brain, pancreas a large number of immature immature