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在遗传学中,早在40年代就认识到化学物质诱发突变。60年代后,各种工业毒物、农药、食品添加剂、化妆品等大量进入人类环境之中,这种环境化学物质对人类体细胞和生殖细胞遗传结构的潜在影响,以及和肿瘤发生、流产、畸胎、遗传性疾病的关系,引起人们的严重关注。测定环境化学物质的诱变力,估计其对人类的潜在遗传危害,提出相应的对策,这是遗传学和毒理学之间的一门新兴的边缘学科——遗传毒理学或毒理遗传学的主要工作内
In genetics, chemical-induced mutations were recognized as early as the 1940s. After the 1960s, a large number of industrial toxicants, pesticides, food additives, cosmetics, etc. entered the human environment, the potential impact of such environmental chemicals on the genetic structure of human somatic and reproductive cells, as well as tumorigenesis, miscarriage, and teratogenesis. The relationship between hereditary diseases and hereditary diseases has caused people’s serious concern. Measuring the mutagenicity of environmental chemicals, estimating their potential genetic hazards to humans, and proposing appropriate countermeasures, this is an emerging marginal discipline between genetics and toxicology – genetic toxicology or toxicology genetics Main work