目的:观察六君子汤对宫颈鳞癌辅助放化疗期间不良反应的影响。方法:将120例患者随机分为2组各60例,对照组单纯予同步放化疗治疗;观察组在同步放化疗期间口服六君子汤治疗,放化疗结束评估疗效。结果:2组生存质量提高情况比较,差异有显著性意义(P<0.05)。放化疗过程中,2组恶心呕吐发生率比较,差异有显著性意义(P<0.05);2组腹泻、血清转氨酶升高、胆红素升高、口腔炎的发生率分别比较,差异均无显著意意义(P>0.05);2组中性粒细胞减少、血红蛋白减少发生率分别比较,差异均有显著性意义(P<0.05);2组血小板减少发生率比较,差异无显著性意义(P>0.05)。结论:口服六君子汤可增强患者对放化疗的耐受力,有利于放化疗的顺利进行,起到增效减毒的作用。 Objective: To observe the effect of Liujunzi Decoction on adverse reactions during adjuvant chemotherapy and radiotherapy for cervical squamous cell carcinoma. Methods: 120 patients were randomly divided into two groups of 60 cases, the control group was treated with concurrent radiotherapy and chemotherapy alone. The observation group was treated with Liujunzitang during concurrent chemoradiotherapy, and the curative effect was evaluated at the end of radiotherapy and chemotherapy. Results: There was significant difference between the two groups in quality of life improvement (P <0.05). During radiotherapy and chemotherapy, the incidence of nausea and vomiting in the two groups was significantly different (P <0.05). There was no difference between the two groups in the incidence of diarrhea, elevated serum transaminase, elevated bilirubin and stomatitis (P> 0.05). There was significant difference in the incidence of neutropenia and hemoglobin decrease between the two groups (P <0.05). There was no significant difference in the incidence of thrombocytopenia between the two groups P> 0.05). Conclusion: Oral Liujunzi decoction can enhance the tolerance of patients to radiotherapy and chemotherapy, is conducive to the smooth progress of radiotherapy and chemotherapy, play a synergistic effect attenuated.