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目的:观察双心室起搏再同步化治疗(CRT)慢性充血性心力衰竭(CHF)患者的临床疗效。方法:选取经药物治疗但逐步加重的CHF患者10(男6,女4)例,年龄(62±10)岁,心功能(NYHA)Ⅲ～Ⅳ级,全部置入双心室三腔起搏器(9例InSyncⅢ8042型,1例FRONTIERⅡ5596型),左室电极置于冠状静脉侧支或后侧支分支内。观察CRT前后左心室功能及体表心电图的变化。结果:10例患者均顺利完成起搏器置入。起搏方式均为心房感知心室起搏,其中总心室起搏数>90%。所有患者的临床指标明显改善,心功能(NYHA)分级、6分钟步行试验、左室射血分数、左室舒末内径、生活质量评分等较术前显著提高(P<0.05,P<0.01)。结论:CRT治疗CHF患者可改善患者心功能,提高生活质量。
Objective: To observe the clinical effect of biventricular pacing resynchronization therapy (CRT) in patients with chronic congestive heart failure (CHF). Methods: A total of 10 (6 males and 4 females) patients with CHF were enrolled in this study. Patients (62 ± 10) years old and NYHA Ⅲ ~ Ⅳ were enrolled in the study. (9 cases of InSync Ⅲ type 8042, 1 case of FRONTIER Ⅱ 5596 type), left ventricular electrode placed in the coronary vein or branch of the dorsal branch. The changes of left ventricular function and surface electrocardiogram before and after CRT were observed. Results: All 10 patients completed pacemaker implantation successfully. Pacing methods are atrial sensing ventricular pacing, in which the total number of ventricular pacing more than 90%. The clinical indexes of all patients were significantly improved. NYHA classification, 6-minute walking test, left ventricular ejection fraction, left ventricular end-diastolic diameter, and quality of life scores were significantly higher than those before operation (P <0.05, P <0.01) . Conclusion: CRT treatment of CHF patients can improve cardiac function and improve quality of life.