大量研究表明前列腺素(prostaglandins,PG)与骨吸收与重建关系密切,因此引起了正畸领域的广泛关注。学者们着重针对PG对功能矫治后的髁突改建和正畸力作用下的牙周组织改建进行了一系列研究。近年来更多的学者开始关注使用药物或生物途径发挥PG利于骨改建的正面作用,抑制其骨破坏的负面作用,取得了一定的效果。正畸治疗中 A large number of studies have shown that prostaglandins (PGs) are closely related to bone resorption and reconstruction, and have drawn wide attention in the field of orthodontics. Scholars focused on a series of studies on the periodontal remodeling of PG under orthodontic force and functional condyle reconstruction. In recent years, more and more scholars have begun to pay attention to the use of drugs or biological pathways to play a positive role in the PG reconstruction of bone to inhibit the negative effects of bone destruction and achieved some results. Orthodontic treatment