宫内节育器(IUD)是一种安全、简便,有效的避孕方法。其作用机制曾有多种学说,但未完全明了。其主要副作用是子宫出血,置器后的内膜,电镜下见浅表层血管有缺口,基底膜断裂;纤溶活性增强;前列腺素增加;酸性磷酸酶及其它溶酶体酶活性增强;并且一些影响血管通透性的因子也增加。以上各种因素综合作用而致子宫出血。 IUD is a safe, easy and effective method of contraception. Its mechanism of action had a variety of theories, but not entirely clear. The main side effect is uterine bleeding, after placement of the endometrium, electron microscopy, superficial blood vessels are notched, basement membrane rupture; fibrinolytic activity increased; prostaglandin increased; acid phosphatase and other lysosomal enzyme activity increased; and some Factors that affect vascular permeability also increase. The combined effects of various factors caused by uterine bleeding.