胃十二指肠溃疡病是世界上最常见的多发病之一,其发病率高达10％左右,但由于其病因至今尚未完全阐明,故其治疗问题颇感辣手。曾风行一时的H_2-受体拮抗剂、如甲氰咪胍等由于它对溃疡病及其出血治疗失败的报告越来越多以及它的明显的副作用,最近又发现有对它不敏感的亚组病人以致使它的应用受到了限 Gastroduodenal ulcer disease is one of the most common and frequently occurring diseases in the world, with a prevalence of up to about 10%. However, due to its etiology has not yet been fully elucidated, so the treatment of the problem is quite hot and spicy. Once popular H 2 -receptor antagonists, such as cimetidine, have been reported to have more and more obvious side effects due to its failure to treat ulcer disease and its hemorrhage and have recently been found to be insensitive to it Group of patients so that its application has been limited