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慢性 T 淋巴细胞白血病(T-CLL)有3种主要类型:①嗜苯胺蓝 T-CLL:②Knobby 型 T-CLL;③成人 T 细胞白血病(ATL)/淋巴瘤。免疫学上Knobby 型 T-CLL 和 ATL 的表现型是 T11+T4~+;而嗜苯胺蓝 T-CLL 主要是 T11+T8~+.嗜苯胺蓝 T-CLL 一般无症状或伴有非进行性疾病的表现,而Knobby 型 CLL 和 ATL 的疾病过程则进展迅速,平均生存期分别为12个月和4.5月。本文报道的是1例兼有嗜苯胺蓝和 Knobby 型 T-CLL 表现的病例。检查骨髓和外周血淋巴细胞表型证明是 T-CLL。采用羊红细胞玫瑰花结法,直接荧光检测 SmIg 及1组单克隆抗体鉴定其免疫学表现型,
There are three main types of T-CLL: ① Aniline blue T-CLL: ② Knobby type T-CLL; ③ Adult T-cell leukemia (ATL) / lymphoma. Immunologically Knobby-type T-CLL and ATL phenotype is T11 + T4 ~ +; and azurophthalide T-CLL is mainly T11 + T8 ~ +. ATS T-CLL generally asymptomatic or associated with non-progressive Disease, while the disease process of Knobby-type CLL and ATL progressed rapidly with an average survival of 12 months and 4.5 months, respectively. This article reports 1 case of both azithromycin and Knobby-type T-CLL manifestations. Check bone marrow and peripheral blood lymphocyte phenotype proved to be T-CLL. The immunological phenotypes were identified by using sheep erythrocyte rosette method, direct fluorescence detection SmIg and monoclonal antibody group 1,