类固醇激素又称甾体激素、包括雌激素,雄激素,孕激素和肾上腺皮质激素。类固醇受体也包括雌激素受体(ER),孕激素受体(PR),雄激素受体(AR),糖皮质激素受体(GR)。受体是存在于效应器细胞膜上或细胞内的生物大分子活性中心,是蛋白质,酶,核酸等物质。构成受体的活性中心主要由阴离子部位和亲脂部位组成。类固醇激素受体的作用机理首先是类固醇激素通过扩散,经过细胞膜进入细膜质,与特异性的受体蛋白结合形成类固醇激素一受体复合物,此复合物在一定条件下发生蛋白质变构,形成与染色体具有高度亲和力的结合部位,转移到核与染色体的DNA结合,激活 Steroid hormones, also known as steroid hormones, including estrogen, androgen, progesterone and adrenal hormones. Steroid receptors also include the estrogen receptor (ER), progesterone receptor (PR), androgen receptor (AR), glucocorticoid receptor (GR). Receptors are biological macromolecule active centers that exist on the cell membrane or in the effector, and are proteins, enzymes, nucleic acids and other substances. The active centers that make up the receptor are mainly composed of anionic sites and lipophilic sites. The mechanism of action of steroid hormone receptor is steroid hormone through diffusion, through the cell membrane into the fine membrane, and the specific receptor protein binding to form a steroid hormone-receptor complex, the complex protein under certain conditions allosteric, Form a binding site with a high affinity for the chromosome, transfer to the nucleus and chromosome DNA binding, activation