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本文报道24个3-取代托品乙醇类、乙烯类和乙烷类化合物的合成。药理筛选结果表明:大多数化合物有明显的抗胆碱能作用,且中枢与外周作用相当。
This article reports the synthesis of 24 3-substituted tropic alcohols, ethers and ethane compounds. Pharmacological screening results show that: most of the compounds have obvious anticholinergic effects, and the central and peripheral role of considerable.