原发性浆细胞性白血病文献报道不多,国外统计其发病率为百万分之一。现报告1例如下。女,49岁,工人,因全身骨痛2个月于1991年1月入院。患者入院前2个月因塞战、高热伴头痛、腰背及骨盆骨疼痛,在外院诊为感染性发热,用青霉素、链霉素,治疗后热退,但骨痛无缓解反而加重而转我院。患病后,体重减轻约5kg,觉疲倦无力,大小便正常。体检:T37℃,神清,面色苍白,全身皮肤无皮疹,无出血点,全身浅表淋巴结无肿大。心肺正常,肝脾无肿大,胸骨下段、头颅骨、腰椎(L_4)、骨盆有轻压痛。神经反射无异常。实验室检查:血象:Hb65g/L,RBC2.08× Primary plasma cell leukemia literature reported little foreign statistics the incidence of one millionth. One report is as follows. Female, 49 years old, worker, admitted to hospital in January 1991 for 2 months due to generalized bone pain. Two months prior to admission, the patients were feverishly infected with penicillin and streptomycin after treatment due to war on stuffing, high fever with headache, back pain and pelvic bone. The patients were treated with penicillin and streptomycin, but they did not relieve the pain but accentuated Our hospital. After illness, weight loss of about 5kg, feeling tired and weak, normal urine. Physical examination: T37 ℃, Shen Qing, pale, systemic skin rash, no bleeding, systemic superficial lymph nodes without swelling. Normal heart and lung, liver and spleen no enlargement, the lower part of the sternum, skull, lumbar (L_4), mild tenderness in the pelvis. Nerve reflex is normal. Laboratory tests: blood: Hb65g / L, RBC2.08 ×