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目的 掌握小儿恶性肿瘤住院化疗过程中的感染状况。方法 对住院化疗的 96例肿瘤患儿的 74 2个疗程进行回顾性调查分析。结果 疗程的感染率为 2 1.4 % ;急性白血病诱导、巩固阶段的感染率分别为 5 0 .8%及4 3.9% ,高于治疗的其他阶段 ;73%的感染患儿血中性粒细胞 <10 0 0 / mm3。结论 小儿恶性肿瘤住院化疗合并感染与化疗的强度及血中性粒细胞数降低有关。
Objective To investigate the infection status of pediatric malignant tumor in hospital during chemotherapy. Methods A retrospective investigation was performed on 74 2 courses of 96 children with chemotherapy admitted to hospital. Results The infection rate was 21.4%. The infection rates during induction and consolidation of acute leukemia were 50.8% and 49.3%, respectively, higher than those in other stages of treatment. In 73% of the infected children, blood neutrophils < 10 0 0 / mm3. Conclusions Admissions for chemotherapy in hospital with chemotherapy for pediatric malignancy are associated with lower intensity of chemotherapy and neutrophil count.