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目的对毛郁金的化学成分进行研究。方法采用硅胶柱色谱、氧化铝柱色谱、ODS柱色谱和制备高效液相色谱等方法分离纯化毛郁金的化学成分,通过波谱数据分析确定化合物的结构。结果从毛郁金乙酸乙酯萃取物中分离得到10个化合物,分别鉴定为莪术二酮(curdione,1)、新莪术二酮(neocurdione,2)、吉马酮-4,5-环氧化物(germacrone-4,5-epoxide,3)、莪术二酮-1,10-环氧化物(curdione-1,10-epoxide,4)、gajutsulactone A(5)、莪术双环烯酮(curcumenone,6)、polydactin B(7)、4,5-seco-4,5-dioxo-guaia-1(10),11-diene(8)、2-endo-hydroxy-1,8-cineole(9)、邻苯二甲酸二丁酯(dibutylphthalate,10)。结论化合物3、5、7-10为首次从该植物中分离得到,其中化合物7-10为首次从姜黄属植物中分离得到。
Objective To study the chemical constituents of hair tulip. Methods Silica gel column chromatography, alumina column chromatography, ODS column chromatography and preparative high performance liquid chromatography (HPLC) were used to separate and purify the chemical components of the hair tulip. The structure of the compounds was confirmed by spectral data analysis. Results Ten compounds were isolated from the ethyl acetate extracts of S. miltiorrhiza and identified as curdione (1), neocurdione (2), germacrone -4,5-epoxide, 3), curdione-1,10-epoxide (4), gajutsulactone A (5), curcumenone (6), polydactin 4,5-dioxo-guaia-1 (10), 11-diene (8), 2-endo-hydroxy- 1,8- cineole (9), phthalic acid Dibutylphthalate (10). Conclusions Compounds 3, 5, 7-10 were isolated from this plant for the first time. Compounds 7-10 were isolated from Curcuma for the first time.