Conditioning knockout of nampt gene in mouse hippocampus neuron induces neuro⁃degeneration and cogni

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OBJECTIVE Nicotinamide phos⁃phoribosyltransferase(NAMPT)is the key en⁃zyme in the NAD(nicotinamide adenine dinucleo⁃tide)salvaging synthesis pathway.The level of NAMPT and NAD decreases during ageing,which causes neurodegenerative diseases.How⁃ever,the st
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