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目的观察双氯芬酸钠栓治疗原发性痛经的临床疗效。方法选择未婚原发性痛经患者90例,随机分为治疗组和对照组各45例。治疗组用双氯芬酸钠栓50 mg塞肛,bid。对照组含服硝苯地平每次10 mg,tid。两组均治疗3 d。3个月经周期为1个疗程。结果治疗组和对照组有效率分别为97.78%,60.0%(P<0.05);复发率分别为6.66%,24.44%(P<0.05);治疗组不良反应明显低于对照组。结论双氯芬酸钠栓治疗原发性痛经具有价廉、使用方便、见效快、复发率低、不良反应小等优点。
Objective To observe the clinical efficacy of diclofenac sodium suppository in the treatment of primary dysmenorrhea. Methods 90 cases of unmarried primary dysmenorrhea were randomly divided into treatment group and control group of 45 cases. The treatment group with diclofenac sodium suppository 50mg plug anal, bid. Control group containing nifedipine 10 mg each time, tid. Both groups were treated for 3 days. 3 menstrual cycle for a course of treatment. Results The effective rates of the treatment group and the control group were 97.78% and 60.0%, respectively (P <0.05). The recurrence rates were 6.66% and 24.44% respectively (P <0.05). The adverse reactions in the treatment group were significantly lower than those in the control group. Conclusion Diclofenac sodium suppository has the advantages of low cost, convenient operation, quick response, low recurrence rate and small adverse reactions.