论文部分内容阅读
目的探讨妊娠早期单纯性甲状腺自身抗体阳性与妊娠晚期出现不良妊娠结局的相关性。方法选取2014年6月至12月在行产前检查的86例妊娠早期孕妇作为研究对象,其中43例甲状腺过氧化物酶抗体(TPOAb)阴性的孕妇作为对照组,43例单纯性TPOAb阳性的孕妇作为试验组,比较两组孕妇妊娠晚期的甲状腺功能异常率及不良妊娠结果发生情况。结果试验组孕妇甲状腺功能异常率为27.9%,明显高于对照组的11.6%,差异有统计学意义(P<0.05);试验组孕妇的不良妊娠率为41.9%,明显高于对照组的18.6%,差异有统计学意义(P<0.05)。结论妊娠早期单纯性甲状腺自身抗体阳性的孕妇在妊娠晚期出现不良妊娠结果的发生率较高,应给予高度重视,及时筛查并予以相关治疗。
Objective To investigate the correlation between the positive thyroid autoantibodies in early pregnancy and the adverse pregnancy outcomes in the third trimester of pregnancy. Methods A total of 86 pregnant women with prenatal pregnancy who were examined prenatally from June 2014 to December 2014 were enrolled in the study. Forty-three pregnant women with negative thyroid peroxidase antibody (TPOAb) were selected as the control group, and 43 simple TPOAb-positive pregnant women Pregnant women as a test group, compared two groups of pregnant women in late pregnancy abnormal thyroid function rate and adverse pregnancy outcomes. Results The abnormal rate of thyroid function in pregnant women in experimental group was 27.9%, which was significantly higher than that in control group (11.6%) (P <0.05). The negative pregnancy rate in pregnant women in experimental group was 41.9%, significantly higher than that in control group %, The difference was statistically significant (P <0.05). Conclusions Pregnant women with simple thyroid autoantibodies in early pregnancy have a higher incidence of adverse pregnancy outcomes in the third trimester of pregnancy. They should be given high priority and be screened and treated accordingly.