目的:探讨膀胱白斑的临床特点及诊断方法,提高诊断水平。方法:分析160例膀胱白斑患者的临床资料。结果:诊断膀胱白斑160例,其中增生型147例,增生、萎缩混合型11例,萎缩型2例。患者膀胱镜检、病理检查、电子显微镜检查可见特征性病理改变。结论:膀胱白斑发病率明显高于文献报道,及时对有间断尿频、尿急、尿痛、血尿、下腹部不适、疼痛的患者进行膀胱镜检,病灶活检是早期发现和诊断膀胱白斑的有效方法。电子显微镜检查可进一步了解病变特点,指导临床诊断治疗。 Objective: To investigate the clinical features and diagnosis of bladder leukoplakia to improve the diagnostic level. Methods: Clinical data of 160 patients with bladder leukoplakia were analyzed. Results: The diagnosis of bladder leukoplakia in 160 cases, of which 147 cases of hyperplasia, hyperplasia, atrophy in 11 cases of mixed, atrophy in 2 cases. Patients with cystoscopy, pathological examination, electron microscopy showed characteristic pathological changes. Conclusions: The incidence of bladder leukoplakia was significantly higher than that reported in the literature. Cystoscopy was performed in patients with intermittent urinary frequency, urgency, dysuria, hematuria, lower abdominal discomfort and pain in time. Fibroblast biopsy was an effective method for early detection and diagnosis of bladder leukoplakia . Electron microscopy can further understand the characteristics of the lesion, to guide the clinical diagnosis and treatment.