啮齿类动物短暂全脑缺血后神经元变性可延迟发生于缺血后2d～3d,但细胞损伤的形态学改变可能要早些。过去普遍认为脑梗死的演变过程于缺血后12 h～24 h可完成,缺血、缺氧后神经细胞死亡是坏死所致。作者对以上观点提出了不同看法。 方法 夹闭LE雄性大鼠双侧颈总动脉及右侧大脑中动脉造成局部缺血-再灌注动物模型。将实验动 Degeneration of neurons after transient global cerebral ischemia in rodents can be postponed 2d ~ 3d after ischemia, but the morphological changes of cell injury may be earlier. In the past generally believed that the evolution of cerebral infarction in 12 h to 24 h after ischemia can be completed, ischemia, hypoxia after nerve cell death is necrosis. The author put forward different views on the above point of view. Methods Closing the bilateral common carotid artery and the right middle cerebral artery of LE male rats caused the model of ischemia-reperfusion. Will experiment