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报道我院14年来诊断为婴儿肝炎综合征(婴肝)住院并死亡的51例病儿。为探讨婴肝患者的肝脏病理改变与死亡的关系,我们对全部病儿进行尸检,并根据肝脏病理变化分以下几型:①重症肝炎:(急性及亚急性)28例(54.90%);②急性肝炎:9例(17.65%);③巨细胞病毒肝炎(CMV):3例(5.88%);④慢性活动性肝炎(CAH):2例(3.92%);⑤胆道闭锁及胆汁性肝硬变:9例(17.65%)。根据上述病理改变明确了婴肝患儿肝脏病变的病因,与国内1991年林氏报道相比,更多了CMV及CAH两型病变,对临床为降低婴肝病死率,在诊治该类病儿时具进一步的参考及指导意义。
Reported in our hospital for 14 years diagnosed as infant hepatitis syndrome (infant liver) hospitalized and died of 51 cases of sick children. To investigate the relationship between liver pathological changes and death in infants with liver diseases, we performed autopsy on all the infants and divided the following types according to the pathological changes of liver: ① Severe hepatitis: 28 cases (54.90%) were acute and subacute ; Acute hepatitis: 9 cases (17.65%); cytomegalovirus hepatitis (CMV): 3 cases (5.88%); chronic active hepatitis (CAH) ⑤ biliary atresia and biliary cirrhosis: 9 cases (17.65%). According to the above pathological changes clear etiology of liver disease in infants with infantile liver disease, compared with the domestic 1991 Lin reported more cases of CMV and CAH type of disease, clinical to reduce the infant mortality, in the diagnosis and treatment of such diseases With further reference and guidance.