Objective:The brain of 100 normal persons were performed MRI scan and image analysis. 12 adult female brain specimens fixed by formalin, were made into the thickness of 0. 5mm by celloidin embedding technique. We analyzed the anatomical position of the relationship about the anterior limb of intal capsule and the anterior commissure in eollodion-embedded plans, and then compared with the brain MRI of normal people. We also further compared the statistical differences of the intal capsule’ s volume. This research aimed to pro-vide a reliable sectional anatomic basis for the study of the central nervous system and deep brain stimulation to treat the mental neurological diseases. Results:1. Continous observation of celloid in brain slices horizontal section:Approximately 130 slices of each specimen, from the parietal lobe,the intal capsule was the typical structure>< on the level of about 35 mm . On the level of about 41mm, the anterior commissure wasarc through the bot-tom head of the caudate nucleus connecting the bilateral anterior limb, which located between the caudate nucleus and the lentiform nucleus. The posterior limb of intal capsule situated between the dorsal thalamus and the lenti-form nucleus on the level of about 46 mm. Coronal section:about 150 slices of per specimen, from the former lat-eral ventricle h back,on the level of about 16 mm the anterior commissure was arch connecting the anterior limb. About 28 mm dimension, the interior capsule fore limb located between the caudate nucleus and the puta-men, the posterior limb of intal capsule located between the globus pallidus and the dorsal thalamus, extending down to the cerebral peduncle. Sagittal section:about 180 slices of per specimen, from the outside to the inside at the beginning of the temporal lobe, the corona radia taextends between the putamen and dorsal thalamus, and then formsthe posterior limb of the intal capsule at the level of about 21 mm. About 25 mm level, fore limb located between the caudate nucleus and the putamen; Genu of the intal capsule located between the caudate nucleus and dorsal thalamus;the posterior limb of intal capsule located between the putamen and the dorsal thalamus, and then extends to the brain stem. 2. The observation of brain MRI images horizontal position: Above the typical level of the intal capsule, intal capsule showed high signal, and the boundaries could be still recognized. Be-low the typical levels of the intal capsule, the globus pallidus and the anterior limb of the intal capsule showed low signal intensity, and both ill-defined, but we could still identify the boundaries of the intal capsule fore limbs. Coronal position: Before the globus pallidus appeared, the tomography of collodion brain slices and brain MRI images were basically the same form. MRI images could be observed clearly that the anterior commissure connected the bilateral the anterior limbs. Sagittal position:The corona radiata was not observed in the MRI ima-ges, and thento switch toward the intal capsule. The emergence of dorsal thalamus and globus pallidus bounda-ries were not observed clearly. 3. Three dimensional reconstruction and analysis of the measurement results The an-atomical structural features of the intal capsule and adjacent structures could be continuously, multi-directional-ly and then dynamically observedon the horizontal, coronal and sagittal plane by three dimensional reconstruction. The anatomical localization of the posterior limb of the intal capsule can be clearly observed in the sagittal plane. The volume data of the left and right intal capsule was statistically significant. Conclusions:1. The experiment described anatomical localization and the three-dimensional model of the intal capsule and anterior commissure in detail, and to provide a reliable basis for the functional anatomy relations between the two follow-up studies. 2. Comparing continuous thin brain slices with the corresponding section of the brain MRI images study, the brain slices collodion show much more clearly than the MRI image about the positional relationship between the intal 180 capsule and adjacent structures. 3. Measurements of the intal capsule and its various divisions on the left and right were statistically significant to provide data support for the asymmetry of brain morphology study.