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本文以黑腹果蝇(Drosophila melanogaster)为材料,用吸入法检测了环氧乙烷(Ethylene Oxide简称EtO)对果蝇生殖细胞3个发育阶段(成熟精子,精细胞和精母细胞)的伴性隐性致死(SLRL)的诱变性。环氧乙烷以气体吸入的方式给果蝇染毒,剂量为900mg/m~3和1800mg/m~3,染毒时间为2h。结果:900mg/m~3和1800mg/m~3对果蝇SLRL总的诱变率pt％分别为1.89％和2.84％,在2种浓度的3个阶段中,均是成熟精子的诱变率最高;精细胞其次;精母细胞最低。总诱变率与自发突变率相比较,显示环氧乙烷对果蝇生殖细胞具有一定的诱变作用。
In this paper, Drosophila melanogaster was used as material to detect the development of three stages of Drosophila germ cells (mature spermatozoa, spermatocytes and spermatocytes) with ethylene oxide (EtO) by inhalation method Sexual Recessive Death (SLRL) Mutagenicity. Ethylene oxide was inhaled into gas to inhale Drosophila at a dose of 900 mg / m ~ 3 and 1800 mg / m ~ 3 for 2 h. Results: The total mutagenicity pT% of SLRL of 900 mg / m ~ 3 and 1800 mg / m ~ 3 were 1.89% and 2.84%, respectively. The mutation rates of mature sperm Highest; sperm cells second; spermatocytes lowest. The total mutagenicity rate compared with the spontaneous mutation rate shows that ethylene oxide has some mutagenic effects on Drosophila germ cells.