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目的:分析不同孕周终止妊娠的早发型重度子痫前期患者的妊娠结局,探讨终止妊娠最佳时机。方法:回顾性分析2008~2009年住院并实施期待疗法的早发型重度子痫前期、终止妊娠孕周>28周的患者119例的临床资料,按终止妊娠孕周分为3组,A组34例为28~31+6周分娩,B组42例为32~33+6周分娩,C组43例为≥34周分娩,比较3组患者的各项临床指标、并发症发生情况及围产儿结局。结果:3组发生胎盘早剥、子痫、心功能衰竭、低蛋白血症等并发症比较差异无统计学意义(P>0.05);新生儿呼吸窘迫综合征(RDS)发生率及围产儿死亡率A组明显高于B、C两组,差异有统计学意义(P<0.05)。结论:早发型重度子痫前期患者孕32周后分娩,早产儿RDS发病率明显下降,孕34周后分娩,围产儿死亡率明显下降。
OBJECTIVE: To analyze the pregnancy outcomes in patients with early-onset severe preeclampsia who have terminated gestational age and to explore the best timing of termination of pregnancy. Methods: The clinical data of 119 patients with early-onset severe preeclampsia and gestational weeks> 28 weeks admitted to hospital from 2008 to 2009 were divided into three groups according to gestational age of termination of pregnancy Cases of childbirth 28 to 31 + 6 weeks, 42 cases of group B 32 ~ 33 + 6 weeks of delivery, 43 cases of group C 34 weeks of delivery, the three groups of patients with clinical indicators, complications and perinatal ending. Results: Complications of placental abruption, eclampsia, heart failure and hypoalbuminemia were not significantly different between the three groups (P> 0.05). The incidence of neonatal respiratory distress syndrome (RDS) and perinatal mortality Rate of A group was significantly higher than B, C two groups, the difference was statistically significant (P <0.05). Conclusions: The incidence of RDS in premature infants with early-onset severe preeclampsia was significantly lower after delivery than that after 32 weeks of pregnancy. After 34 weeks of pregnancy, the mortality rate of perinatal infants was significantly decreased.