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1.多氯联苯的毒代动力学研究多氯联苯(PCBs)广泛存在于芬兰外界环境中,不仅有职业性与事故性接触,而且还可通过鱼类食品进入人体。用高效反向气相色谱法(GC/examinecontainers)可测定人体血清与各种组织中的PCBs。芬兰非接触工人的参考限值为3μg/L。用SIMCA模型鉴别方法可识别不同接触来源的(环境、事故与职业)PCBs的各种异构体,发现脂肪组织中3-、4-和5-三种氯联苯比血清中高出4~80倍,6-、7-两种氯联苯高出14~200倍;当事故性接触时,血清与脂肪组
1. Toxicokinetic studies of polychlorinated biphenyls Polychlorinated biphenyls (PCBs) are widely present in the Finnish environment and are not only exposed to occupational and accidental exposures but also enter the human body through fish food. PCBs in human serum and various tissues can be assayed by GC / Examiners. The reference limit for non-exposed workers in Finland is 3 μg / L. Identification of various isomers of (environmental, accident and occupational) PCBs from different sources of exposure using the SIMCA model identification method revealed that 3-, 4- and 5- chlorobiphenyls in adipose tissue were 4 to 80% higher than serum Times, 6-, 7- two kinds of PCBs higher than 14 to 200 times; when accidental contact, serum and fat group