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β肾上腺素能阻滞剂已广泛应用,主要用于治疗心绞痛或高血压。自1966年用心得安作嗜铬细胞瘤的症状治疗后,发现此药使某些病人的血压明显升高。现已证明,非嗜铬细胞瘤病人应用β肾上腺素能阻滞剂亦可引起显著高血压。二者用α肾上腺素能阻滞剂降压均有效。作者观察44例精神病患者口服心得安并迅速增大剂量至脉率降至58～62次/分,血压90/60毫米汞柱左右,其中8例血压升高,部分病例在血压升高前数小时有血管收缩,精神紧张等先兆,有2例血压突然升
β-adrenergic blockers have been widely used, mainly for the treatment of angina or hypertension. Since the treatment of symptoms of pheochromocytoma with phentolamine in 1966, it has been found that this medicine significantly increases the blood pressure in some patients. It has been shown that non-pheochromocytoma patients with β-adrenergic blockers can also cause significant hypertension. Both use of alpha-adrenergic blockers are effective antihypertensive. The authors observed 44 cases of psychiatric patients oral propranolol and rapidly increased the dose to the pulse rate dropped to 58 to 62 beats / min, blood pressure 90/60 mm Hg or so, of which 8 cases of elevated blood pressure, some cases before the blood pressure increased Hours of vasoconstriction, mental stress and other aura, 2 cases of sudden increase in blood pressure