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目的探讨米非司酮配伍卡孕栓和米索前列醇片阴道给药应用于大月份钳刮术前准备的效果。方法 81例行钳刮术大月份妊娠患者,随机分为对照组(40例)与观察组(41例)。对照组在口服米非司酮的基础上采用卡孕栓阴道给药,观察组在口服米非司酮的基础上采用米索前列醇片阴道给药。观察两组患者的用药效果。结果两组宫颈扩张程度、宫颈软化时间、阴道流血量对比差异均无统计学意义(P>0.05),观察组给药次数、用药费用均明显优于对照组,差异均具有统计学意义(P<0.05)。观察组不良反应发生率0低于对照组47.5%,差异具有统计学意义(P<0.05)。结论米非司酮配伍米索前列醇片阴道给药应用于大月份钳刮术前准备的效果显著,明显优于配伍卡孕栓,值得临床推广。
Objective To investigate the effect of mifepristone compatibility with captopril and misoprostol vaginal administration in the preparation of large month forceps. Methods Eighty-one patients undergoing clamp curettage in the first month of pregnancy were randomly divided into control group (n = 40) and observation group (n = 41). The control group received oral administration of carboplatin on the basis of oral administration of mifepristone. The observation group was given vaginal administration of misoprostol on the basis of oral administration of mifepristone. Observation of two groups of patients medication effect. Results There was no significant difference between the two groups in the degree of cervical dilation, cervical softening time and vaginal bleeding (P> 0.05), and the number of administration and cost of medication in the observation group were significantly better than those in the control group (P <0.05). The incidence of adverse reactions in the observation group 0 was 47.5% lower than that in the control group, the difference was statistically significant (P <0.05). Conclusion The combination of mifepristone and misoprostol for vaginal delivery in the large-month pliersurgical operation has significant effect, which is obviously better than compatibility with carbamazepine, which is worthy of clinical promotion.