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目的探讨肝病并发自发性细菌性腹膜炎的发病因素、诊治及预后。方法收集安徽中医学院第一附属医院68例肝病患者并发自发性细菌性腹膜炎临床及实验室资料作回顾性分析,其中38例为肝硬化患者,12例为原发性肝癌患者,18例为重型肝炎患者。结果 68例患者中临床表现以发热为主(89.7%),多数患者腹水多形核白细胞明显升高(86.8%),腹水培养阳性率低(19.1%),头孢类抗生素疗效佳,其中死亡16例(23.5%)。结论 SBP是肝病晚期的严重并发症,临床表现不典型,综合的分析与及时的诊断与治疗对于预后有着举足轻重的作用。
Objective To investigate the pathogenesis, diagnosis, treatment and prognosis of liver disease complicated with spontaneous bacterial peritonitis. Methods The clinical and laboratory data of 68 cases of liver disease complicated with spontaneous bacterial peritonitis were collected from the First Affiliated Hospital of Anhui College of Traditional Chinese Medicine for retrospective analysis. Among them, 38 were liver cirrhosis patients, 12 were primary liver cancer patients and 18 were heavy-duty Hepatitis patients. Results The clinical manifestations in 68 patients were mainly fever (89.7%). Most patients had a marked increase in ascites polymorphonuclear leukocytes (86.8%), a low positive rate of ascites culture (19.1%), and a good effect of cephalosporin antibiotics, of which 16 Example (23.5%). Conclusion SBP is a serious complication of advanced liver disease and its clinical manifestations are not typical. Comprehensive analysis and timely diagnosis and treatment play an important role in prognosis.