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目的:探究硫辛酸联合前列地尔治疗糖尿病周围神经病变的效果。方法:采用随机数字表法将112例糖尿病患者随机分为2组,对照组采用常规治疗方法进行糖尿病的治疗,治疗组在对照组的基础上加用硫辛酸和前列地尔,对比治疗后2组患者肢体运动神经传导速度(MNCV)、肢体感觉神经传导速度(SNCV)、神经病变感觉症状问卷(TSS)评分以及视觉模拟评分(VAS)。结果:治疗后治疗组患者的MNCV、SNCV、TSS及VAS相比对照组均得到显著改善,P<0.05。结论:硫辛酸联合前列地尔治疗糖尿病周围神经病变效果显著,值得临床推广。
Objective: To investigate the effect of lipoic acid combined with alprostadil on diabetic peripheral neuropathy. Methods: One hundred and twelve patients with diabetes mellitus were randomly divided into two groups using random number table method. The control group was treated with conventional therapy for diabetes mellitus. The treatment group was given lipoic acid and alprostadil on the basis of the control group. After 2 The motor nerve conduction velocity (MNCV), limb sensory nerve conduction velocity (SNCV), neuropathy sensory symptoms questionnaire (TSS) and visual analogue scale (VAS) were measured in the group of patients. Results: After treatment, the MNCV, SNCV, TSS and VAS in the treatment group were significantly improved compared with the control group (P <0.05). Conclusion: Lipoic acid combined with alprostadil treatment of diabetic peripheral neuropathy significant effect, worthy of clinical promotion.