口服黑色素瘤较少见。以往国内外学者发表的有关文章中极少见牙龈黑色素瘤的专门论述。我们在2485例龈活检资料的回顾性分析中发现龈黑色素瘤15例,现简要报告如下。 材料和方法 龈黑色素瘤15例均为牙龈临床活检或手术后标本。标本用10％福尔马林固定,石蜡包埋、切片、切片厚度5～6μm,常规HE染色。用光学显微镜观察,并复习临床病史。 Oral melanoma is rare. In the past articles published by scholars at home and abroad, there was very little special mention of gingival melanoma. In a retrospective analysis of 2485 cases of biopsy data, we found 15 cases of melanoma, and the summary report is as follows. Materials and Methods 15 cases of melanoma were clinical biopsy or postoperative specimens of gingiva. Specimens were fixed in 10% formalin, paraffin-embedded, sectioned, and sectioned to a thickness of 5-6 μm for routine HE staining. Observe with an optical microscope and review the clinical history.