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急性冠状动脉综合征( ACS)目前仍然是内科疾病中最急危重症之一。尽管近年来各种预防及治疗措施的不断改进使得该病的发病率和病死率显著下降，但该类患者一旦发病仍面临较高的复发率及病死率。经皮冠状动脉介入( PCI)手术治疗ACS的效果优良，但并非所有ACS患者都能实施手术治疗，相当一部分患者出于各种原因只能通过药物保守治疗。该文就ACS患者非血运重建治疗，即单纯药物治疗的进展予以综述。“,”Patients with acute coronary syndrome ( ACS) remain one of the highest-risk disease among acute medical admissions. Despite significant reduction in morbidity and mortality via refinements in treat-ment in recent years,some individuals remain at a high risk of recurrent ischemic events and death. The effi-ciency of Percutaneous Coronary Intervention( PCI) has already been confirmed effective by a large amount of clinical trials,but not all the patients with ACS can be remedied by the operation of PCI,a considerable num-ber of patients could only be treated by drugs for some reasons. This article will review the development of the non-revascularization therapy,namely simple drug treatment,in ACS patients.