以高脂饲料喂45只家兔,对其中26只于13～17周后出现肺动脉和支气管动脉粥样硬化者作了肺组织和冠状动脉的病理学观察。肺组织肉眼观察见肺动脉总干、左、右肺动脉及其分支均有粥样硬化,病变尤其好发于肺动脉总干及其分叉处,呈黄色点状、细条状或境界清楚的脂质斑块。光镜下可见肺动脉病灶内含大量泡沫细胞,类脂浸润,平滑肌细胞和弹力纤维增生。9只家兔的肺内支气管动脉壁有与肺动脉内相似的粥样硬化病变。电镜下可见肺动脉内皮下间隙中平滑肌绍胞增生和大量泡沫细胞形成, Forty-five rabbits were fed high-fat diet, and pathological observation of lung and coronary arteries was performed on 26 of them at 13-17 weeks after pulmonary and bronchial atherosclerosis. Macroscopic observation of pulmonary tissue seen in the total dry pulmonary artery, left and right pulmonary artery and its branches are atherosclerosis, lesions occur especially in the general and the bifurcation of the pulmonary artery, yellow spots, thin strips or clear the state of the lipid plaque Piece. Light microscopy showed a large number of pulmonary artery lesions containing foam cells, lipid infiltration, smooth muscle cells and elastic fiber hyperplasia. In nine rabbits, the pulmonary bronchial artery wall had similar atherosclerotic lesions in the pulmonary artery. Electron microscopy showed pulmonary artery subcutaneous interstitial smooth muscle cell proliferation and a large number of foam cell formation,