端粒是真核细胞染色体末端特有的重复结构,由(AAT-GGG)n组成,能够防止染色体发生降解及端-端融合,在细胞分裂时,由于染色体自身缺陷,随着细胞分裂次数的增加其端粒逐渐缩短,最终使细胞进入危险期,并导致细胞死亡而在许多恶性肿瘤及其相应的细胞中,当端粒酶呈阳性表达时,则肿瘤 Telomeres are unique repetitive structures at the end of eukaryotic chromosomes and consist of (AAT-GGG) n, which prevents chromosomal degradation and end-to-end fusion. As cells divide, due to their own chromosomal defects, as the number of cell divisions increases The telomeres progressively shortened, eventually leading the cell to a dangerous phase and leading to cell death, whereas in many malignancies and their corresponding cells, when telomerase is positively expressed, the tumor