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目的了解2014年甘肃口岸朝觐归国人员呼吸道病毒感染情况,重点监测中东呼吸综合征(MERS)及流感等呼吸道传染病病原流行情况。方法采集甘肃口岸朝觐人员入境检疫查验中发现流感样病例咽拭子样本84份,通过世界卫生组织(WHO)推荐的荧光定量RT-PCR方法检测中东呼吸综合征相关病毒,同时针对病毒RNA样本开展甲、乙型流感病毒、甲型H1N1流感病毒、甲型H3流感病毒、甲型H5N1流感病毒、甲型H7N9流感病毒、冠状病毒NL63型、HKU1型、229E型、OC43型、人博卡病毒、人偏肺病毒、呼吸道合胞病毒进行检测。结果所有样本均未检出中东呼吸综合征病毒,有9份样本检出其他12种病原核酸的其中1种,分别为甲型H3N2流感病毒(5例)、冠状病毒(3例)、偏肺病毒(1例),病毒总检出率为10.7%,其中甲型流感病毒检出率最高,为5.9%。呼吸道传染病病毒阳性病例以老年人(≥60岁)为主,在性别分布上无差异。结论 2014年甘肃口岸归国朝觐人员未检出MERS病毒感染,具有流感样病例的朝觐归国人员主要以甲型流感病毒为呼吸道传染病病原,并以老年人为主,初步掌握甘肃口岸朝觐归国人员病毒性呼吸道传染病病原谱组成,为开展朝觐人员健康保障工作提供参考。
Objective To understand the status of respiratory virus infection among pilgrimages returning from Gansu Port in 2014 and to monitor the prevalence of respiratory infectious diseases such as Middle East respiratory syndrome (MERS) and influenza. Methods Eighty-four swab samples of influenza-like illness were collected from quarantine inspection of pilgrims in port of Gansu province. Middle East respiratory syndrome virus was detected by the fluorescence quantitative RT-PCR method recommended by World Health Organization (WHO), and at the same time, Influenza A, Influenzavirus A, Influenza A H1N1, Influenzavirus H3, Influenza A H5N1, Influenza A H7N9, Coronavirus NL63, HKU1, 229E, OC43, human Boka, Human metapneumovirus, respiratory syncytial virus detection. Results None of the samples were detected in the samples of the Middle East Respiratory Syndrome virus. Nine samples detected one of the 12 other pathogenic nucleic acids, namely, influenza A (H3N2) virus (5), coronavirus (3) Virus (1 case), the total virus detection rate was 10.7%, of which the highest detection rate of influenza A virus was 5.9%. Respiratory infectious virus positive cases of the elderly (≥ 60 years) dominated, no difference in gender distribution. Conclusions MERS virus infection was not detected in Haizun pilots returning to Gansu port in 2014. The Hajj pilgrims with flu-like cases mainly used influenza A virus as the pathogen of respiratory tract infection and were mainly elderly people. They initially mastered the return of pilgrimage to the Gansu port It also provides a reference for the health protection of pilgrims.