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目的探讨辛伐他汀联合阿司匹林治疗急性缺血性脑卒中的疗效。方法选取我院收治的急性缺血性脑卒中患者120例进行回顾性分析,随机分成观察组和对照组各60例,观察组采用辛伐他汀联合阿司匹林治疗,对照组仅采用阿司匹林治疗,观察两组在血脂各项指标、ADL评分、ESS评分和治疗效果上的不同。结果治疗前后两组血脂各项指标均有显著下降,且观察组下降水平显著优于对照组,存在统计学意义(P<0.05);治疗前后两组ADL和ESS评分均有显著变化,观察组变化显著优于对照组,存在统计学意义(P<0.05);观察组治疗效果明显优于对照组,存在统计学意义(P<0.05)。结论辛伐他汀联合阿司匹林治疗急性缺血性脑卒中效果显著,能够有效降低血脂水平,改善神经功能和日常生活能力,值得临床推广。
Objective To investigate the efficacy of simvastatin combined with aspirin in the treatment of acute ischemic stroke. Methods A total of 120 patients with acute ischemic stroke admitted to our hospital were retrospectively analyzed and randomly divided into observation group (60 cases) and control group (60 cases). The observation group was treated with simvastatin combined with aspirin, while the control group was treated with aspirin Group in the indicators of blood lipids, ADL score, ESS score and treatment effect on the different. Results Before and after treatment, the indexes of blood lipid in both groups decreased significantly, and the decrease in the observation group was significantly better than that in the control group (P <0.05). ADL and ESS scores of both groups changed significantly before and after treatment. The observation group (P <0.05). The curative effect of the observation group was obviously better than that of the control group, with statistical significance (P <0.05). Conclusion Simvastatin combined with aspirin treatment of acute ischemic stroke significant effect, can effectively reduce blood lipid levels, improve nerve function and daily living ability, is worth clinical promotion.