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甲状腺髓样癌占甲状腺癌的5~10%。有散发和家族性两类,后者易获早期诊断和治疗,有常染色体显性遗传的特征。因力病例少和缺少未经治疗的病例报导,故其自然病程难以预测。它的恶性程度是介于分化好和差的甲状腺癌之间。已有转移者,可迅速发展而致命。在晚期,无论起病年龄、性别、民族、疾病的程度和治疗方法都很少影响其最终的结果,但估计宿主的免疫反应可影响其预后。甲状腺髓样癌的前躯细胞是C细胞(Parafollicular cell),它可分泌异常高
Medullary thyroid cancer accounts for 5 to 10% of thyroid cancer. There are two types of sporadic and familial, the latter easily accessible for early diagnosis and treatment, characterized by autosomal dominant inheritance. Due to the small number of cases and lack of untreated case reports, the natural history of the disease is difficult to predict. Its degree of malignancy is between well differentiated and poor thyroid cancer. Those who have already transferred can develop rapidly and become fatal. In the later stages, regardless of the onset age, sex, ethnicity, extent of disease, and treatment method, their final results are rarely affected, but it is estimated that the host’s immune response may affect its prognosis. The precursor cell of medullary thyroid carcinoma is a C-cell (Parafollicular cell), which can secrete abnormally high