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目的：观察葛根素注射液治疗冠心病心绞痛的疗效及其安全性。方法：采用随机双盲对照法分为治疗组３０例（男性１１例，女性１９例，年龄６２±ｓ１１ａ），对照组２０例（男性１２例，女性８例，年龄６６±１２ａ），治疗组以葛根素注射液３００ｍｇ（对照组仅为该注射液的溶剂）加于５％葡萄糖液５００ｍＬ中静脉滴注，ｑｄ，１０ｄ为一个疗程。结果：治疗组对症状的总有效率９７％，心电图总有效率６０％，高于对照组的４５％，３０％，（Ｐ＜０．０１，Ｐ＜０．０５），治疗组并有降低血液粘度、血小板聚集率和改善左室舒张功能的作用，而对照组则无上述效应，２组均未见显著不良反应。结论：葛根素注射液是一种安全有效的抗心肌缺血药物。
Objective: To observe the curative effect and safety of puerarin injection on angina pectoris of coronary heart disease. Methods: Randomized double-blind control group was divided into treatment group 30 cases (11 males and 19 females, age 62 ± s11a), the control group of 20 patients (12 males and 8 females, age 66 ± 12a), the treatment group To puerarin injection 300mg (control group only the solvent of the injection) plus 5% glucose solution 500mL intravenous infusion, qd, 10d for a course of treatment. Results: The total effective rate of the treatment group was 97%, the total effective rate of ECG was 60%, which was higher than that of the control group (45%, 30%, P <0.01, P <0.05) Blood viscosity, platelet aggregation rate and the effect of improving left ventricular diastolic function, while the control group did not have the above effects, two groups were no significant adverse reactions. Conclusion: Puerarin Injection is a safe and effective anti-ischemic drug.