论文部分内容阅读
目的探讨华蟾素注射液联合肝动脉化学药物栓塞(TACE)治疗原发性肝癌(肝癌)近期疗效。方法将43例肝癌患者随机分为两组,治疗组(华蟾素注射液加TACE)21例,对照组(单纯TACE)22例。观察患者治疗前后临床主要症状的变化。结果治疗组和对照组的显效、无效,分别6、9、3例和3、5、11例,治疗组总有效率(77%)显著优于对照组(51.37%)(P<0.05),两组治疗后AFP比治疗前均有下降,但治疗组优于对照组(P<0.01),且生活质量评分明显改善。结论华蟾素联合肝动脉栓塞化疗可以有效延长患者的生命,改善生活质量,对失去手术机会的肝癌患者是有效方法之一。
Objective To investigate the short-term curative effect of cinobufagin injection combined with hepatic arterial chemoembolization (TACE) in the treatment of primary liver cancer (HCC). Methods Forty-three HCC patients were randomly divided into two groups: 21 cases in the treatment group (Cinobufagin injection plus TACE) and 22 cases in the control group (TACE alone). Observed before and after treatment in patients with major clinical changes. Results The total effective rate (77%) in the treatment group and the control group was significantly better than that in the control group (51.37%) (P <0.05), 6,9,3 cases and 3,5,11 cases respectively. AFP decreased after treatment in both groups, but the treatment group was better than the control group (P <0.01), and the quality of life score was significantly improved. Conclusion Cinobufacini combined with transcatheter arterial chemoembolization can effectively prolong the life of patients and improve the quality of life. It is an effective method for patients with liver cancer who have lost the chance of operation.