论文部分内容阅读
目的探讨骨质疏松性胸腰椎压缩骨折经皮椎体后凸成形(PKP)术后新发椎体骨折的危险因素。方法回顾性分析自2012-11—2014-10采用PKP治疗的161例骨质疏松性椎体压缩骨折,根据PKP术后是否出现椎体新发骨折,分为未骨折组(148例)和新发骨折组(13例)。结果术后随访时间,即新发椎体骨折时间距PKP术后0.93~22.97(11.93±6.97)个月。161例中13例(16个椎体)出现新发椎体骨折,新发骨折发生率8.07%。单因素分析发现,新发骨折组与未骨折组在吸烟史、椎体高度恢复率、骨密度、骨水泥渗漏方面差异有统计学意义(P<0.05),在年龄、性别、骨水泥注入量、椎体骨折数、骨折发病季节等方面差异无统计学意义(P>0.05)。多因素Logistic回归分析显示,骨质疏松程度重、骨水泥渗漏是PKP术后新发椎体骨折的危险因素(P<0.05)。结论骨质疏松程度重、骨水泥渗漏是骨质疏松性胸腰椎压缩骨折PKP术后新发椎体骨折的危险因素,PKP术中应尽可能减少骨水泥渗漏,术后应规范抗骨质疏松治疗。
Objective To investigate the risk factors of new vertebral fractures after osteoporotic thoracolumbar compression fractures after percutaneous kyphoplasty (PKP). Methods A total of 161 osteoporotic vertebral compression fractures treated with PKP from 2012-11-2014-10 were retrospectively analyzed. According to whether new fractures of vertebral body occurred after PKP, the fractures were divided into non-fracture group (148 cases) and new fracture group Fracture group (13 cases). Results The postoperative follow-up time was 0.93 ~ 22.97 (11.93 ± 6.97) months after PKP. In 161 cases, 13 cases (16 vertebrae) had new vertebral fractures, and the incidence of new fractures was 8.07%. Univariate analysis showed that there were significant differences in smoking history, vertebral height recovery rate, bone mineral density and bone cement leakage between the new fracture group and the non-fracture group (P <0.05) Volume, vertebral fractures, the incidence of fractures and other aspects of the difference was not statistically significant (P> 0.05). Multivariate logistic regression analysis showed that the severity of osteoporosis and bone cement leakage were risk factors for new vertebral fractures after PKP (P <0.05). Conclusions The degree of osteoporosis and bone cement leakage are the risk factors of new vertebral fractures after PKP of osteoporotic thoracolumbar compression fractures. The leakage of cement should be reduced as much as possible during PKP, Loose treatment.